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The CLF Research Registry

Pledge Your Brain to Science

The CLF Research Registry comprises the Brain Donation Registry (BDR) and the Clinical Research Registry (CRR).

CLF Research Registry

Join the CLF Research Registry

Help Accelerate Research

The CLF Research Registry comprises the Brain Donation Registry (BDR) and the Clinical Research Registry (CRR). You may sign up for one or both.

CLF Canada is proud to collaborate with the Canadian Concussion Centre at the Toronto Western Hospital, as well as members of the CLF Global Brain Bank.

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Research Resources

Browse our Brain Donation FAQ for more information. For imminent brain donation matters, please visit our Imminent Brain Donation page or contact the respective brain banks directly.

Imminent Brain Donation
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Brain Donation FAQ
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About the CLF Global Brain Bank
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About Clinical Research
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GET INVOLVED

Join the CLF Research Registry

Brain donation is a generous act that helps raise awareness for concussion and CTE research and allows your family to know your wishes for brain donation after death. Brain Donation Registry members will receive an informational packet on brain donation. Please note: your pledge is non-binding and pledging your brain does not guarantee your brain will be studied due to the natural evolution of research.

If you have an urgent inquiry regarding a recent or imminent death, please visit our Imminent Brain Donation page.

By signing up for the Clinical Research Registry, you’ll help accelerate clinical research studies on brain injuries and CTE led by research institutions across Canada.

Register today to begin receiving information on active studies for which you may be a fit. Thank you in advance for committing your time and effort to these important studies.

Have Questions?

Research & Brain Donation FAQ

In 2023, the Concussion Legacy Foundation Canada partnered with the Canadian Concussion Centre to advance CTE research in Canada. This collaboration is led by Dr. Gabor Kovacs and Dr. Carmela Tartaglia. For more about the Canadian Concussion Centre and our global collaborators, including the impact that brain donation has had on our understanding of CTE, head to our brain banks page.

Research is the key that unlocks our ability to prevent and treat the effects of brain trauma. Clinical research on human volunteers allows scientists to pick up on changes in the brain that lead to CTE while someone is alive, bringing us closer to being able to diagnose CTE during life. The Concussion Legacy Foundation Canada actively recruits for studies led by researchers across Canada. For more information on active studies, head to our clinical research page.

For legal reasons, your pledge is not binding; the final decision to donate will be made by your next of kin. Therefore, it is essential to discuss your intent to donate with your family.
No. All expenses involved with brain donation and participation in the research program are covered by the brain bank. Please note that funeral expenses remain the responsibility of your family.
The autopsy procedure does not interfere with the events associated with the funeral. No disfigurement occurs as a result of this procedure. The family can plan an open casket or other traditional funeral arrangements and the donation process will be undetectable. In addition, we will do our best not to interfere with any arrangements the family might have.
Over the course of several months, scientists will examine your brain tissue for evidence of injury, TBI, CTE, and any other disorders. Clinicians will interview members of your family designated by your next of kin to learn your medical, sports, and military history. Clinical and pathological results will be reviewed by a team of doctors and researchers, who will arrive at a consensus diagnosis. Finally, together with our doctors, we will personally communicate the results to your next of kin via conference call.

CTE is a global problem, but due to a lack of brain tissue, few researchers outside the United States were able to study this devastating disease. The Concussion Legacy Foundation founded the CLF Global Brain Bank to activate scientists from every corner of the globe in the fight against CTE. Led by some of the world’s greatest researchers on brain trauma and CTE, the CLF Global Brain Bank has collaborators in Australia, Brazil, New Zealand, the United Kingdom, and the United States, with plans for future growth. For more information about the CLF Global Brain Bank and the importance of brain donation around the world, visit our brain banks page.

After you pledge to donate your brain, you will receive a virtual brain donor card. Share the donor card and brochure with your family and let them know of your wishes.
In the event of your passing, your next of kin will follow instructions on your brain donor card to call the 24-hour emergency donation pager at 647.535.2021. The donation coordinator will arrange the tissue collecting by a local diener near the locality where the donor has died. The donation process is a time-sensitive matter; if the brain bank team is not alerted within 48 hours the donation may not be possible. For instructions on what to do in the case of a recent or imminent death, please visit our Imminent Brain Donation page.
The next of kin is required to complete consent forms authorizing brain, spinal cord, and CSF and/or plasma donation. These will be faxed or emailed by the brain donation coordinator.
Due to the natural evolution of research, we cannot guarantee in advance that the Canadian Concussion Centre will be able to accept your donation. The Brain Donation coordinator will make that determination based on the current inclusion criteria at the time of death. As of 2025, the Canadian Concussion Centre needs brain donations from current and retired professional and amateur athletes as well as members of the public who have suffered repeated concussions, including military Veterans. However, research needs and research funding evolve, and we cannot predict future criteria.
Large group of people at the Race To End CTE 2023 event

SUPPORT OUR MISSION

Help Us End Brain Injury.Donate Today.

Your contribution directly fuels life-saving research and provides essential support to kids, Veterans, caregivers, athletes and families across Canada facing the challenges of brain injuries.

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